Currently the FDA HAS NOT approved any at-home or self-test kits. For information on tests that have been revoked see Historical Information about Device Emergency Use Authorizations: In Vitro Diagnostics (IVD). The impacts of flu, COVID-19, and respiratory syncytial virus have underscored the importance of having tests . Before sharing sensitive information, make sure you're on a federal government site. SARS-CoV-2 Viral Mutations: Impact on COVID-19 Tests. There's a new federal resource to get free FDA-authorized coronavirus test kits. 1 Authorized settings include the following: 2 Authorization Documents include the Healthcare Provider (HCP) and Patient Fact Sheets and either the Manufacture Instructions/Package Insert (abbreviated to IFU) or the EUA Summary. Members of the public can submit questions about the templates to CDRH-EUA-Templates@fda.hhs.gov, or they can submit comments regarding the templates to the public docket established for the guidance Policy for Coronavirus Disease-2019 Tests (Revised). Lab has notified Laboratory Field Services that it performs COVID-19 testing via the COVID-19 Notification Form. Antigen multi-analyte respiratory panel tests authorized in the table below are assigned the QMN product code. Most Food and Drug Administration approved at-home COVID tests have a longer lifespan than previously anticipated. 263a, that meet requirements to perform high complexity tests. Abbott Diagnostics Scarborough, Inc.:BinaxNOW COVID-19 Ag Card Home Test, Abbott Diagnostics Scarborough, Inc.:BinaxNOW COVID-19 Antigen Self Test, Access Bio, Inc.:CareStart COVID-19 Antigen Home Test, ACON Laboratories, Inc:Flowflex COVID-19 Antigen Home Test, Aptitude Medical Systems Inc.:Metrix COVID-19 Test, Becton, Dickinson and Company (BD):BD Veritor At-Home COVID-19 Test, Celltrion USA, Inc.:Celltrion DiaTrust COVID-19 Ag Home Test, CTK Biotech, Inc.:ImmuView COVID-19 Antigen Home Test, Cue Health Inc.:Cue COVID-19 Test for Home and Over The Counter (OTC) Use, Genabio Diagnostics Inc.:Genabio COVID-19 Rapid Self-Test Kit, iHealth Labs, Inc.:iHealth COVID-19 Antigen Rapid Test, InBios International Inc:SCoV-2 Ag Detect Rapid Self-Test, Lucira Health, Inc:Lucira CHECK-IT COVID-19 Test Kit, Maxim Biomedical, Inc.:MaximBio ClearDetect COVID-19 Antigen Home Test, Mologic, Inc.:COVI-Go SARS-CoV-2 Ag Self-Test, OraSure Technologies, Inc.:InteliSwab COVID-19 Rapid Test, PHASE Scientific International, Ltd.:INDICAID COVID-19 Rapid Antigen At-Home Test, Quidel Corporation:QuickVue At-Home OTC COVID-19 Test, SD Biosensor, Inc.:Pilot COVID-19 At-Home Test 1, Siemens Healthineers:CLINITEST Rapid COVID-19 Antigen Self-Test, Watmind USA:Speedy Swab Rapid COVID-19 Antigen Self-Test, Xiamen Boson Biotech Co., Ltd.:Rapid SARS-CoV-2 Antigen Test Card, ANP Technologies, Inc.:NIDS COVID-19 Antigen Home Test, Beijing Hotgen Biotech Co., Ltd.:Hotgen COVID-19 Antigen Home Test, Azure Biotech Inc.:Fastep COVID-19 Antigen Home Test, Oceanit Foundry LLC:ASSURE-100 Rapid COVID-19, Advin Biotech Inc.:Advin COVID-19 Antigen Test @Home, GenBody Inc.:GenBody COVID-19 Ag Home Test, Lucira Health, Inc.:Lucira COVID-19 & Flu Home Test, An official website of the United States government, : Travel . Find All FDA-Approved Home and Lab Tests You can find information about each home or lab test that FDA has approved or cleared by searching FDA's Database of In Vitro Diagnostic (IVD). The FDA has updated expiration dates for those tests. Expired at-home COVID tests can lead to inaccurate or invalid test results, but medical experts say to think twice before throwing them away. Authorized by the FDA for at-home use in November 2021, the iHealth at-home COVID antigen test comes with two nasal swabs, test cassettes, fluid vials, and vial caps. For more information about this, read our FDA Safety Communication. This action is in response to available data about the performance of COVID-19 antigen tests showing that repeat testing after a negative COVID-19 antigen test result increases the chance of an accurate result in people with and without symptoms and could help prevent people from unknowingly spreading the SARS-CoV-2 virus to others. For details about each authorized COVID-19 diagnostic test, see the lists of authorized Molecular Diagnostic Tests and Antigen Diagnostic Tests, as well as the At-Home COVID-19 Diagnostic Tests webpage. Since the start of. Warner-Lambert, which merged with Pfizer in 2000, . After embedding information warfare sailors and officers aboard two subs, there are now talks "to invest full-time, probably, in . The TGA has approved the following COVID-19 self-tests (home use tests) for supply in Australia from 1 November 2021. COVID-19 Testing Update: Today, our administration announced that beginning January 15, 2022, individuals covered by a health insurance plan who purchase an FDA-approved, over-the-counter COVID-19 . The prevalence, and remaining unknowns, of the omicron variant have put people on edge and sent them out for testing in numbers that have caused the site at Barnett Park in Orange County to hit capacity hours before the it was scheduled to close two days in a row. Availability: This test is available online with or without a prescription, SELF explained previously.To get it, you'll first have to fill out a survey to make sure you meet the criteria for . The Food and Drug Administration prohibited 65 manufacturers from selling masks for medical use. You can use the Test Type drop down box to select a Type of Test. H - Laboratories certified under the Clinical Laboratory Improvement Amendments of 1988 (CLIA), 42 U.S.C. FDA Advisory No.2021-2094 || List of COVID-19 Test Kits with FDA Special Certification and Performance Validation Conducted and/or Recommended by the Research Institute for Tropical Medicine (RITM) - Food and Drug Administration designed to detect more than one section of the proteins that make up SARS-CoV-2; more likely to continue to perform as labeled as new variants emerge. UPDATE. If potential impacts are identified, the EUA holder must communicate with the FDA and end users about the potential risk that presence of the mutations may have on test performance. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely. Before sharing sensitive information, make sure you're on a federal government site. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely. For additional performance information about EUA authorized serology/antibody tests, please see the EUA Authorized Serology Test Performance page. The Ohio State University Wexner Medical Center. In certain circumstances, one test type may be recommended over the other. Molecular tests are more. It does not detect the virus. Before sharing sensitive information, make sure you're on a federal government site. 8/24/2021. HCP, Recipients, IFU-ARCHITECT, IFU-Alinityi. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely. Sara Humm, the senior planner with the Columbia/Boone County Public Health and Human Services said originally, the at-home tests had an expiration date between four and six months. You can also use an FDA-authorized at-home COVID-19 diagnostic test which gives you the option of self-testing where it is convenient for you. Once you've confirmed your vitamin D levels via testing, adjust your sun exposure and/or vitamin D3 supplementation accordingly. Blood samples are only used to test for antibodies and not to diagnose COVID-19. Jonas Edward Salk (/ s l k /; born Jonas Salk; October 28, 1914 - June 23, 1995) was an American virologist and medical researcher who developed one of the first successful polio vaccines.He was born in New York City and attended the City College of New York and New York University School of Medicine.. The most common sample types are: Swab samples use a swab (similar to a long Q-Tip) to collect a sample from the nose or throat. dba MicroGen DX, Columbia University Laboratory of Personalized Genomic Medicine, BioFire Respiratory Panel 2.1 (RP2.1) - On March 17, 2021, FDA granted the first marketing authorization using the De Novo review pathway for the. Serology tests could play a role in the fight against COVID-19 by helping healthcare professionals identify individuals who may have developed an immune response to SARS-CoV-2. There are two types of COVID-19 diagnostic tests, molecular and antigen, which detect different parts of the virus. An extended expiration date means the manufacturer provided data showing that the shelf-life is longer than was known when the test was first authorized. These include molecular tests,. As new tests are authorized for use, they are added to these tables so that anyone can access up-to-date information on all authorized tests and collection kits. M - Laboratories certified under the Clinical Laboratory Improvement Amendments of 1988 (CLIA), 42 U.S.C. Be sure to check the At-Home OTC COVID-19 Diagnostic Tests website for information on expiration dates, who can use the test, and other details that may help you decide what test is right for you. Online, if you click to . The FDA authorized three COVID-19 vaccines (Pfizer, Moderna and Johnson & Johnson) to answer an urgent need to protect people from the coronavirus pandemic, which was (and continues to be) a public health emergency. People with symptoms that began within the last 7 days. Health Canada 50.5%. A few weeks ago, a ProPublica reporter decided to test his kids for COVID-19. Alternate brand name: GoodToKnow COVID-19 Antigen Rapid Test, Alternate brand name: GoToKnow COVID-19 Antigen Rapid Test, Alternate brand name: QuickFinder COVID-19 Antigen Self Test. The shelf-life is how long the test should work as expected and is measured from the date the test was manufactured. vaccines accepted will include FDA approved or authorized and WHO Emergency Use Listing vaccines. COVID-19 Tests and Collection Kits Authorized by the FDA The FDA is committed to helping ensure the public has access to a wide variety of test options for COVID-19. There are two common types of COVID-19 diagnostic tests: Molecular tests, such as polymerase chain reaction (PCR) and other nucleic acid amplification tests (NAATs) tests, which detect. The standard regimen is the FDA-approved dosing regimen. The site is secure. The newly authorized tests in the fight against COVID-19 are Abbott's BinaxNOW test and Quidel's QuickVue. Another way to find the updated list of expiration dates is on the FDA's website. <section jsaction="rcuQ6b: trigger.EGZ8Jb" jscontroller="ThIs3" jsshadow class="XzbSje m586Kb JGNgFd VLrnY eO2Zfd " aria-labelledby="_ypbgzc_i1 _Eq2Xzc_i2" data . The Centers for Disease Control and Prevention (CDC) has granted a right of reference to the performance data contained in CDC's EUA request (FDA submission number EUA200001) to any entity seeking an FDA EUA for a COVID-19 diagnostic device. Beijing Wantai Biological Pharmacy Enterprise Co., Ltd. GK Pharmaceuticals Contract Manufacturing Operations, Real-time RT-PCR, Saliva, Pooling, Multiple Targets, Real-time RT-PCR, Multiple Targets, Pooled Serial Screening Media, RT-PCR and MALDI-TOF Mass Spec. Understanding COVID-19 tests, including the different types of tests and their uses, and the types of samples the tests use, is key to making an informed decision that meets your needs. To see if the expiration date for your at-home OTC COVID-19 test has been extended, first find the row in the below table that matches the manufacturer and test name shown on the box label of your test. Before sharing sensitive information, make sure you're on a federal government site. Coronavirus Disease 2019 (COVID-19) Emergency Use Authorizations for Medical Devices, Recalls, Market Withdrawals and Safety Alerts, Coronavirus Disease 2019 (COVID-19) Emergency Use Authorizations for Medical Devices, Continuous Renal Replacement Therapy and Hemodialysis Devices EUAs, Remote or Wearable Patient Monitoring Devices EUAs, Ventilators and Ventilator Accessories EUAs, Emergency Use Authorizations for Medical Devices, In Vitro Diagnostics EUAs - Antigen Diagnostic Tests for SARS-CoV-2, Molecular Diagnostic Tests for SARS-CoV-2, Serology and Other Adaptive Immune Response Tests for SARS-CoV-2, Individual EUAs for Antigen Diagnostic Tests for SARS-CoV-2, Antigen EUA Revisions for Serial (Repeat) Testing, Historical Information about Device Emergency Use Authorizations: In Vitro Diagnostics (IVD), INDICAID COVID-19 Rapid Antigen At-Home Test, Letter Granting EUA Revision(s) (May 12, 2022), Letter Granting EUA Revision(s) (August 12, 2022), Letter Granting EUA Revision(s) (December 22, 2022), Letter Granting EUA Revision(s) (March 7, 2022), Letter Granting EUA Revision(s) (April 28, 2022), Letter Granting EUA Revision(s) (June 24, 2022), Letter Granting EUA Revision(s) (October 14, 2022), Letter Granting EUA Revision(s) (March 29, 2022), Letter Granting EUA Revision(s) (April 4, 2022), Letter Granting EUA Revision(s) (July 8, 2022), Letter Granting EUA Revision(s) (January 11, 2023), Letter Granting EUA Revision(s) (November 4, 2022), Letter Granting EUA Revision(s) (January 20, 2023), Letter Granting EUA Revision(s) (October 15, 2021), Letter Granting EUA Revision(s) (April 20, 2022), Letter Granting EUA Revision(s) (September 2, 2022), Letter Granting EUA Revision(s) (November 18, 2022), Letter Granting EUA Revision(s) (August 24, 2022), Letter Granting EUA Amendment(s) (June 9, 2020), Letter Granting EUA Amendment(s) (July 17, 2020), Viral MutationRevision Letter - September 23, 2021, BD Veritor System for Rapid Detection of SARS-CoV-2, Letter Granting EUA Amendment(s) (July 23, 2020), Letter Granting EUA Revision(s) (December 10, 2021), Letter Granting EUA Revision(s) (January 26, 2021), Letter Granting EUA Revision(s) (February 17, 2022), Letter Granting EUA Revision(s) (April 6, 2021), Letter Granting EUA Revision(s) (January 7, 2022), Letter Granting EUA Revision(s) (February 4, 2022), Letter Granting EUA Revision(s) (November 21, 2022), Letter Granting EUA Revision(s) (March 15, 2021), Letter Granting EUA Revisions(s) (July 16, 2021), Letter Granting EUA Revision(s) (December 2, 2021), Letter Granting EUA Revision(s) (January 17, 2023), VITROS Immunodiagnostic Products SARS-CoV-2 Antigen Reagent Pack, Letter Granting EUA Revision(s) (November 16, 2021), BD Veritor System for Rapid Detection of SARS-CoV-2 & Flu A+B, Letter Granting EUA Revision(s) (July 21, 2022), Letter Granting EUA Revision(s) (September 23, 2022), Letter Granting EUA Revision(s) (December 21, 2022), Letter Granting EUA Revision(s) (July 12 2021), Letter Granting EUA Revision(s) (February 16, 2022), Letter Granting EUA Revision(s) (October 25, 2022), Celltrion DiaTrust COVID-19 Ag Rapid Test, Letter Granting EUA Revision(s) (August 11, 2022), Letter Granting EUA Revision(s) (March 3, 2022), Letter Granting EUA Revision(s) (May 26, 2022), Letter Granting EUA Revision(s) (December 23, 2022), Sienna-Clarity COVID-19 Antigen Rapid Test Cassette, Letter Granting EUA Revision(s) (December 17, 2021), Letter Granting EUA Revision(s) (June 09, 2022), Letter Granting EUA Revision(s) (August 3, 2022), Letter Granting EUA Revision(s) (February 01, 2023), Letter Granting EUA Revision(s) (June 13, 2022), Letter Granting EUA Revision(s) (February 21, 2023), Letter Granting EUA Revision(s) (January 14, 2022), Letter Granting EUA Revision(s) (February 22, 2022), Letter Granting EUA Revision(s) (December 28, 2022), Letter Granting EUA Revision(s)(August 23, 2021), Letter Granting EUA Revision(s) (January 22, 2022), Letter Granting EUA Revisions(s) (June 7, 2022), Letter Granting EUA Revision(s) (August 29, 2022), Letter Granting EUA Revision(s) (September 28, 2022), Letter Granting EUA Revision(s) (Feburary 1, 2022, CLINITEST Rapid COVID-19 Antigen Self-Test, Letter Granting EUA Revision(s) (June 23, 2022, Letter Granting EUA Revision(s) (October 12, 2022), Letter Granting EUA Revision(s) (December 27, 2022), MaximBio ClearDetect COVID-19 Antigen Home Test, Letter Granting EUA Revision(s) (March 30, 2022), Letter Granting EUA Revision(s) (July 22, 2022), Letter Granting EUA Revision(s) (December 16, 2022), Letter Granting EUA Revision(s) (January 09, 2023), Letter Granting EUA Revision(s) (May 4, 2022), Letter Granting EUA Revision(s) (December 2, 2022), Letter Graning EUA Revision(s) (February 24, 2023), ADVIA Centaur SARS-CoV-2 Antigen (CoV2Ag), Letter Granting EUA Revision(s) (August 19, 2022), Letter Granting EUA Revision(s) (October 18, 2022), Speedy Swab Rapid COVID-19 Antigen Self-Test, Letter Granting EUA Revision(s) (August 23, 2022). BinaxNOW, however,. This page provides information on types of COVID-19 Tests and Supplies for laboratory personnel. As such, KOMU 8 is the only major network affiliate in the United States that acts as a university-owned commercial television station utilizing its newsroom as a working lab for students. For more information about antibody testing, visit Antibody (Serology) Testing for COVID-19: Information for Patients and Consumers. This article's lead section may be too long for the length of the article. Please keep in mind that merely contacting Nelson Mullins Riley & Scarborough LLP will not establish an attorney-client relationship. Diagnostic Covid tests fall into two buckets: molecular tests and antigen tests. On November 1, 2022, the FDA revised the authorized uses and required updates to product labeling regarding repeat, or serial, testing, for all currently authorized SARS-CoV-2 antigen tests. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely. You can read more about the individual types of tests, safety communications and how to interpret your test results at the links below: The FDA encourages health care professionals and patients to report adverse events or side effects as well as performance issues related to the use of COVID-19 tests or other medical products to the FDAs MedWatch Safety Information and Adverse Event Reporting Program: Subscribe to receive FDA Consumer Update email notifications. ; ; Catal; Cymraeg; Deutsch; Eesti; ; Espaol; Euskara; ; Franais; ; ; Hrvatski . The most important thing to consider when looking for an updated expiration date is the brand or manufacturer of the at-home COVID test. (August 2022) People with symptoms that began within the last 7 days. The FDA said it has authorized over 400 COVID-19 tests and collection kits - 235 molecular, 88 antibody, and 34 antigen tests -- to help ensure the public has access to a wide variety of. At-Home COVID-19 Antigen Tests-Take Steps to Reduce Your Risk of False Negative, Lateral Flow, Visual Read, Over the Counter (OTC) Home Testing, Serial Screening, Single Target, Lateral Flow, Visual Read, Over the Counter (OTC) Home Testing, Serial Screening, Single Target,Telehealth Proctor Supervised (optional), Lateral Flow, Visual Read, Over the Counter (OTC) Home Testing, Serial Screening, Multiple Targets, Lateral Flow, Visual Read, Serial Screening, Single Target, Lateral Flow, Digital Read, Over the Counter (OTC) Home Testing, Serial Screening, Single Target, Lateral Flow, Fluorescence, Instrument Read, Serial Screening, Single Target, Chromatographic Digital Immunoassay, Instrument Read, Serial Screening, Single Target, Microfluidic Immunofluorescence Assay, Instrument Read, Serial Screening, Single Target, Lateral Flow, Visual Read, Single Target, Serial Screening, Lateral Flow, Fluorescence, Instrument Read, Multi-Analyte, Single Target, Magnetic Force-assisted Electrochemical Sandwich Immunoassay (MESIA), Single Target, Lateral flow immunoluminescent assay, instrument read, Serial Screening, Single Target, Lateral Flow, Fluorescence, Instrument Read, Over the Counter (OTC) Home Testing, Serial Screening, Single Target, Lateral Flow, Visual Read, Over the Counter (OTC) Home Testing, Telehealth Proctor Supervised, Serial Screening, Single Target, Chemiluminescence Immunoassay, Instrument Read, Single Target, Lateral Flow, Visual Read, Multi-analyte, Single Target, Lateral Flow, Visual Read, Prescription Home Testing, Single Target, Chromatographic Digital Immunoassay, Instrument Read, Multi-analyte, Single Target, Bulk Acoustic Wave (BAW) Biosensor, Instrument Read, Serial Screening, Single Target, Lateral Flow, Visual Read, Serial Screening, Multiple Targets, Lateral Flow, Visual Read, Over the Counter (OTC) Home Testing, Serial Screening, Single Target, Lateral Flow, Visual Read, Serial Screening, Single Target, Lateral Flow, Fluorescence, Instrument Read, Single Target, Lateral Flow, Visual Read,Serial Screening, Single Target, Digital Lateral Flow, Fluorescence, Instrument Read, Single Target, Lateral Flow, Visual Read, Over the Counter (OTC) Home Testing, Serial Testing, Serial Screening, Single Target. Buy BinaxNOW Covid19 Antigen Self $19.88. Appendix J - Sample Updated Fact Sheet for Health Care Providers, Appendix K - Sample Updated Fact Sheet for Patients, EUA Letter of Authorization - Umbrella EUA for SARS-CoV-2 Molecular Diagnostic Tests for Serial Testing, Appendix L - Fact Sheet for Health Care Providers (Template), Appendix M - Fact Sheet for Patients (Template), Laboratories Who Have Developed a Molecular-Based Test (LDTs) for Coronavirus Disease 2019 (COVID-19), Orig3n 2019 Novel Coronavirus (COVID-19) Test, Biocollections Worldwide SARS-Co-V-2 Assay, Avera Institute for Human Genetics SARS-CoV-2 Assay, Real-time RT-PCR, Home Collection, Saliva, Multiple Targets, RT, LAMP, Over the Counter (OTC) Home Testing, Saliva, Screening, Multiple Targets, Real-time RT-PCR, Home Collection, Multiple Targets, Screening, Pooling, Laboratory Corporation of America (Labcorp), Direct to Consumer (DTC), Real-time RT-PCR, Multi-analyte, Home Collection, Single Target, End-Point RT-PCR, Screening, Multiple Targets, Home Collection Kit, Screening, Single Target, Real-time RT-PCR, Home Collection, Screening, Multiple Targets, RT, LAMP, Lateral Flow Strips, Over the Counter (OTC) Home Testing, Serial Screening, Single Target, Real-time RT-PCR, Multi-analyte, Multiple Targets, Cleveland Clinic Robert J. Tomsich Pathology and Laboratory Medicine Institute, Real-time RT-PCR, Multi-analyte, Home Collection, Multiple Targets, Yale School of Public Health, Department of Epidemiology of Microbial Diseases, Direct to Consumer (DTC), Real-time RT-PCR, Saliva, Home Collection, Screening, Pooling, Single Target, Direct to Consumer (DTC), Home Collection Kit, Saliva, Screening, Real-time RT-PCR, Home Collection, Multiple Targets, The Mount Sinai Hospital, Center for Clinical Laboratories, Real-time RT-PCR, Home Collection, Saliva, Screening, Multiple Targets, Centers for Disease Control and Prevention's (CDC), Real-time RT-PCR, Pooling, Multiple Targets, Wadsworth Center, New York State Department of Public Health, RT-PCR and electrochemical detection, Single Target, Real-time RT-PCR, Home Collection, Pooling, Multiple Targets, Real-time RT-PCR, Home Collection, Pooling, Screening, Multiple Targets, Real-time RT-PCR, Pooling, Screening, Multiple Targets, RT, Nested multiplex PCR, Pooling, Saliva, Multiple Targets, Real-time RT-PCR, Pooling, Screening, Saliva, Multiple Targets, RT, Isothermal amplification, Single Target, RT-PCR, Collection Kit, Saliva, Multiple Targets, RT-PCR, CoPrimer technology, Single Target, Real-time RT-digital PCR, Multiple Targets, Real-time RT-PCR, Screening, Multiple Targets, RT, Isothermal amplification, Multiple Targets, RT-PCR, Home Collection, Saliva, Single Target, Fast Track Diagnostics Luxembourg S..r.l. Some, but not all manufacturers of approved rapid antigen tests (RATs) have extended the shelf-life of their products. Since the start of the pandemic, we authorized over 400 tests and collection kits, including: For more information, please visit fda.gov/medical-devices. In a statement, the agency is urging people to stop using the LuSys Laboratories COVID-19 Antigen Test and the LuSys Laboratories COVID-19 IgG/IgM Antibody Test. Click here for a full list of FDA approved at-home COVID tests and their up-to-date expiration dates. Walmart. For three weeks . During the discussion, Watters asked DeSantis to respond to Donald Trump's comments about him in recent weeks. "There's a page on their website where you can look up by the name of the test, and see what that expiration date extension is," Humm said. SAN DIEGO Pilot projects launched last year to examine how information warfare gurus can enhance submarine operations may yield long-term plans. Please read the layout guide and lead section guidelines to ensure the section will still be inclusive of all essential details. They give your result in a few minutes and are different from .
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